Calcitonin gene-related peptide involved in migraine from trigeminovascular system

A recent article points to the use of CRCP (Calcitonin gene-related peptide) antagonists to treat migraines. Levels of CGRP rise during migraine and experimentally injecting IV CRCP can provoke migraine. Two CGRP antagonists are being tested inthe study from Acta Neurol Belg. 2009 Dec;109(4):252-61.CGRP is produced by the trigeminovascular system. Many patients who undergo treatment with a